منابع مشابه
Biomarker for Antidepressant Response
A novel dopamine and norepinephrine reuptake inhibitor (DNRI), dasotraline, appears to be an effective treatment for adults with ADHD, according to results of a placebo-controlled clinical study presented at the American College of Neuropsychopharmacology Annual Meeting. The agent, still in development, inhibits presynaptic dopamine and norepinephrine reuptake. It has a half-life suggestive of ...
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OBJECTIVE The study aims were 1) to describe the proportions of individuals who met criteria for melancholic, atypical, and anxious depressive subtypes, as well as subtype combinations, in a large sample of depressed outpatients, and 2) to compare subtype profiles on remission and change in depressive symptoms after acute treatment with one of three antidepressant medications. METHOD Particip...
متن کاملPredicting Factors of Depression, Antidepressant Use and Positive Response to Antidepressants in Perinatal and Postpartum Women
BACKGROUND In the United States, there is a disparity in knowledge of nationwide depression prevalence, the antidepressant use and the antidepressant responses during perinatal/postpartum periods. OBJECTIVE This study investigated the predicting factors of depression, antidepressant use and positive antidepressant response during the perinatal/postpartum periods. METHOD The 2007-2012 Nation...
متن کاملBiomarkers Predicting Antidepressant Treatment Response: How Can We Advance the Field?
Major depression, affecting an estimated 350 million people worldwide, poses a serious social and economic threat to modern societies. There are currently two major problems calling for innovative research approaches, namely, the absence of biomarkers predicting antidepressant response and the lack of conceptually novel antidepressant compounds. Both, biomarker predicting a priori whether an in...
متن کاملSustained antidepressant response to ketamine.
Case series outlining the treatment of three patients with ketamine, in which two of the patients had a sustained antidepressant effect to ketamine without the need for maintenance on antidepressants. These two responders have an established diagnosis of bipolar affective disorder with a history of response to electroconvulsive therapy and lithium, both of which have an influence on the seizure...
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ژورنال
عنوان ژورنال: Nature Reviews Neuroscience
سال: 2008
ISSN: 1471-003X,1471-0048
DOI: 10.1038/nrn2346